5i67: Difference between revisions
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==Crystal Structure Analysis of MTB PEPCK mutant C273S== | |||
<StructureSection load='5i67' size='340' side='right' caption='[[5i67]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5i67]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5I67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5I67 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5i67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5i67 OCA], [http://pdbe.org/5i67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5i67 RCSB], [http://www.ebi.ac.uk/pdbsum/5i67 PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PCKG_MYCTA PCKG_MYCTA]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dostal, J]] | [[Category: Dostal, J]] | ||
[[Category: Machova, I]] | |||
[[Category: Pachl, P]] | |||
[[Category: Pichova, I]] | |||
[[Category: Snasel, J]] | [[Category: Snasel, J]] | ||
[[Category: | [[Category: Lyase]] | ||
[[Category: | [[Category: Mutant c273]] | ||
[[Category: | [[Category: Pepck]] | ||