5hsz: Difference between revisions
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==Structure of the K. pneumonia SlmA protein bound to the C-terminal tail of the cytoskeletal cell division protein FtsZ== | |||
<StructureSection load='5hsz' size='340' side='right' caption='[[5hsz]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5hsz]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HSZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HSZ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hsz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hsz OCA], [http://pdbe.org/5hsz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hsz RCSB], [http://www.ebi.ac.uk/pdbsum/5hsz PDBsum]</span></td></tr> | ||
[[Category: Schumacher, M | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/SLMA_KLEP7 SLMA_KLEP7]] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Schumacher, M A]] | |||
[[Category: Zeng, W]] | [[Category: Zeng, W]] | ||
[[Category: Cell cycle]] | |||
[[Category: Cell division]] | |||
[[Category: Cytokinesis]] | |||
[[Category: Ftsz]] | |||
[[Category: Nucleoid occlusion]] | |||
[[Category: Slma]] | |||
[[Category: Z-ring]] | |||
Revision as of 11:29, 12 May 2016
Structure of the K. pneumonia SlmA protein bound to the C-terminal tail of the cytoskeletal cell division protein FtsZ
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