4zt7: Difference between revisions
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==Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-N'-(5-fluoro-3H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1717)== | |||
<StructureSection load='4zt7' size='340' side='right' caption='[[4zt7]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4zt7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZT7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZT7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4RC:N-[(4R)-6,8-DICHLORO-1,2,3,4-TETRAHYDROQUINOLIN-4-YL]-N-(5-FLUORO-3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PROPANE-1,3-DIAMINE'>4RC</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAS:S-(DIMETHYLARSENIC)CYSTEINE'>CAS</scene></td></tr> | ||
[[Category: Hol, W | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zt6|4zt6]], [[4zt5|4zt5]], [[4zt4|4zt4]], [[4zt3|4zt3]], [[4zt2|4zt2]]</td></tr> | ||
[[Category: Koh, C | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zt7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zt7 OCA], [http://pdbe.org/4zt7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zt7 RCSB], [http://www.ebi.ac.uk/pdbsum/4zt7 PDBsum]</span></td></tr> | |||
</table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Methionine--tRNA ligase]] | |||
[[Category: Hol, W G.J]] | |||
[[Category: Koh, C Y]] | |||
[[Category: Aar]] | |||
[[Category: Aminoacyl-trna synthetase]] | |||
[[Category: Ligase]] | |||
[[Category: Ligase-ligase inhibitor complex]] | |||
[[Category: Metr]] | |||
[[Category: Protein-inhibitor complex]] | |||
[[Category: Trypanosoma brucei]] | |||
Revision as of 19:34, 13 May 2016
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor N-[(4R)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-N'-(5-fluoro-3H-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (Chem 1717)
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