Nitroreductase: Difference between revisions
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<StructureSection load='1icr' size='350' side='right' caption='E. coli nitroreductase dimer containing FMN and nicotinic acid (PDB entry [[1icr]])' scene=''> | <StructureSection load='1icr' size='350' side='right' caption='E. coli nitroreductase dimer containing FMN and nicotinic acid (PDB entry [[1icr]])' scene=''> | ||
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== Relevance == | == Relevance == | ||
NR is of special interest due to its potential use as activator of prodrugs in cancer therapy. | |||
== Structural highlights == | == Structural highlights == | ||
NR cofactor FMN is bound to one subunit while the ligand - nicotinic acid - interacts with both subunits. | |||
</StructureSection> | </StructureSection> | ||
