5a0w: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5a0w is ON HOLD until Paper Publication~~

==THE CRYSTAL STRUCTURE OF I-DMOI E117A IN COMPLEX WITH ITS TARGET DNA AND IN THE PRESENCE OF 2MM MN==

~~Authors: Molina, R., Besker, N., Prieto, J., Montoya, G., D'Abramo, M.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5a0w]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0W OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A0W FirstGlance].

~~Description:~~ THE CRYSTAL STRUCTURE OF I-DMOI E117A IN COMPLEX WITH ITS TARGET DNA AND IN THE PRESENCE OF 2MM MN

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5a0m|5a0m]]</td></tr>

[[Category: D'Abramo, M]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0w OCA], [http://pdbe.org/5a0w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a0w RCSB], [http://www.ebi.ac.uk/pdbsum/5a0w PDBsum]</td></tr>

[[Category: ~~Prieto~~, J]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/DMO1_DESMO DMO1_DESMO]] Endonuclease involved in intron homing. Recognizes a recognizes up to 20 bp of DNA in the 23S rRNA gene intron. It has a slow turnover rate and cuts the coding strand with a slight preference over the non-coding strand.

__TOC__

</StructureSection>

[[Category: Abramo, M D]]

[[Category: Besker, N]]

[[Category: Molina, R]]

~~[[Category: Besker, N]]~~

[[Category: Montoya, G]]

[[Category: Prieto, J]]

[[Category: Gene targeting]]

[[Category: Genetic]]

[[Category: Homing endonuclease]]

[[Category: Hydrolase-dna complex]]

[[Category: Protein-dna interaction]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5a0w is ON HOLD  until Paper Publication
+==THE CRYSTAL STRUCTURE OF I-DMOI E117A IN COMPLEX WITH ITS TARGET DNA AND IN THE PRESENCE OF 2MM MN==
+<StructureSection load='5a0w' size='340' side='right' caption='[[5a0w]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-Authors: Molina, R., Besker, N., Prieto, J., Montoya, G., D'Abramo, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5a0w]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A0W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A0W FirstGlance]. <br>
-Description: THE CRYSTAL STRUCTURE OF I-DMOI E117A IN COMPLEX WITH ITS TARGET DNA AND IN THE PRESENCE OF 2MM MN
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a0m|5a0m]]</td></tr>
-[[Category: D'Abramo, M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a0w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a0w OCA], [http://pdbe.org/5a0w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a0w RCSB], [http://www.ebi.ac.uk/pdbsum/5a0w PDBsum]</span></td></tr>
-[[Category: Prieto, J]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DMO1_DESMO DMO1_DESMO]] Endonuclease involved in intron homing. Recognizes a recognizes up to 20 bp of DNA in the 23S rRNA gene intron. It has a slow turnover rate and cuts the coding strand with a slight preference over the non-coding strand.
+__TOC__
+</StructureSection>
+[[Category: Abramo, M D]]
+[[Category: Besker, N]]
 [[Category: Molina, R]]
-[[Category: Besker, N]]
 [[Category: Montoya, G]]
+[[Category: Prieto, J]]
+[[Category: Gene targeting]]
+[[Category: Genetic]]
+[[Category: Homing endonuclease]]
+[[Category: Hydrolase-dna complex]]
+[[Category: Protein-dna interaction]]