Dicer: Difference between revisions
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==Structure== | ==Structure== | ||
Human Dicer (hDicer) is a <scene name='70/706244/4nh3_dimer/1'>dimer</scene>. Each chain is a large multidomain enzyme whose C-terminal half includes a PAZ domain, a pair of tandem RNase III domains, and a double-stranded RNA-binding domain. There are four <scene name='70/706244/Mg_2eb1/1'>magnesium</scene> ions that bind to the | Human Dicer (hDicer) is a <scene name='70/706244/4nh3_dimer/1'>dimer</scene>. Each chain is a large multidomain enzyme whose C-terminal half includes a PAZ domain, a pair of tandem RNase III domains, and a double-stranded RNA-binding domain. There are four <scene name='70/706244/Mg_2eb1/1'>magnesium</scene> ions that bind to the hDicer RNase IIIb homodimer. There are oxygen ligands bonded to each Magnesium, which create an <scene name='70/706244/Mg_2eb1/2'>octahedral</scene> geometry on each Magnesium. | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
