|
|
| Line 1: |
Line 1: |
| ==Crystal structure of MetRS in complex with 2-({3-[(3,5-dichlorobenzyl)amino]propyl}amino)quinolin-4(1H)-one==
| | #REDIRECT [[5k0s]] This PDB entry is obsolete and replaced by 5k0s |
| <StructureSection load='4lne' size='340' side='right' caption='[[4lne]], [[Resolution|resolution]] 2.45Å' scene=''>
| |
| == Structural highlights ==
| |
| <table><tr><td colspan='2'>[[4lne]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Brucella_melitensis_biovar_abortus_2308 Brucella melitensis biovar abortus 2308]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LNE FirstGlance]. <br>
| |
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0OU:2-({3-[(3,5-DICHLOROBENZYL)AMINO]PROPYL}AMINO)QUINOLIN-4(1H)-ONE'>0OU</scene></td></tr>
| |
| <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAB1_1014, metG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=359391 Brucella melitensis biovar Abortus 2308])</td></tr>
| |
| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr>
| |
| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lne FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lne OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lne RCSB], [http://www.ebi.ac.uk/pdbsum/4lne PDBsum]</span></td></tr>
| |
| </table>
| |
| == Function ==
| |
| [[http://www.uniprot.org/uniprot/Q2YQ76_BRUA2 Q2YQ76_BRUA2]] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity).[HAMAP-Rule:MF_01228][SAAS:SAAS023457_004_015657]
| |
| __TOC__
| |
| </StructureSection>
| |
| [[Category: Brucella melitensis biovar abortus 2308]]
| |
| [[Category: Methionine--tRNA ligase]]
| |
| [[Category: Structural genomic]]
| |
| [[Category: Ligase]]
| |
| [[Category: Metr]]
| |
| [[Category: Ssgcid]]
| |
This PDB entry is obsolete and replaced by 5k0s
