5bow: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5bow ~~is ON HOLD until Paper Publication~~

==CRYSTAL STRUCTURE OF IL-38==

~~Authors~~: ~~Guenther, S~~.~~, Sundberg, E~~.J.

== Structural highlights ==

<table><tr><td colspan='2'>[[5bow]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOW OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BOW FirstGlance].

~~Description~~: ~~CRYSTAL STRUCTURE OF IL~~-38

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4ize|4ize]], [[1md6|1md6]], [[1ilr|1ilr]]</td></tr>

[[~~Category~~: ~~Sundberg~~, E.J]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bow OCA], [http://pdbe.org/5bow PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bow RCSB], [http://www.ebi.ac.uk/pdbsum/5bow PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/IL1FA_HUMAN IL1FA_HUMAN]] Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.<ref>PMID:22315422</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Guenther, S]]

[[Category: Sundberg, E J]]

[[Category: Beta trefoil]]

[[Category: Innate immune signaling]]

[[Category: Signaling protein]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5bow is ON HOLD  until Paper Publication
+==CRYSTAL STRUCTURE OF IL-38==
+<StructureSection load='5bow' size='340' side='right' caption='[[5bow]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
-Authors: Guenther, S., Sundberg, E.J.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5bow]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BOW FirstGlance]. <br>
-Description: CRYSTAL STRUCTURE OF IL-38
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ize|4ize]], [[1md6|1md6]], [[1ilr|1ilr]]</td></tr>
-[[Category: Sundberg, E.J]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bow OCA], [http://pdbe.org/5bow PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bow RCSB], [http://www.ebi.ac.uk/pdbsum/5bow PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/IL1FA_HUMAN IL1FA_HUMAN]] Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.<ref>PMID:22315422</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Guenther, S]]
+[[Category: Sundberg, E J]]
+[[Category: Beta trefoil]]
+[[Category: Innate immune signaling]]
+[[Category: Signaling protein]]