Eukaryotic initiation factor: Difference between revisions

From Proteopedia
Jump to navigationJump to search
No edit summary
No edit summary
Line 1: Line 1:
<StructureSection load='1ipb' size='350' side='right' scene='50/507723/Cv/1' caption='Human initiation factor EIF4E complex with 7-methyl GPPPA [[1ipb]]'>
<StructureSection load='1ipb' size='450' side='right' scene='50/507723/Cv/1' caption='Human initiation factor EIF4E complex with 7-methyl GPPPA [[1ipb]]'>
   
   
== Function ==
== Function ==
Line 11: Line 11:
== Structural insights ==
== Structural insights ==


EIF domains include the N terminal domain (NTD), C terminal domain (CTD), RNA recognition domain, middle domain, PAZ domain of EIF2C and a protein-protein interaction domain (PCI) of EIF3.
EIF domains include the N terminal domain (NTD), C terminal domain (CTD), RNA recognition domain, middle domain, PAZ domain of EIF2C and a protein-protein interaction domain (PCI) of EIF3.  
 
*<scene name='50/507723/Cv/3'>P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE (7-methyl GPPPA) binding site</scene>. Water molecules shown as red spheres.
   
   
</StructureSection>
</StructureSection>