Outer surface protein: Difference between revisions
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'''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. '''OspA''' contributes to the colonization of the gut by the bacteria. '''OspC''' | '''Outer surface proteins''' (Osp) are produced by the bacteria Borrelia burgdorferi which causes Lyme disease. OspA and OspB are upregulated when the bacteria enter the tick. '''OspA'''<ref>PMID:10953031</ref> contributes to the colonization of the gut by the bacteria. '''OspB'''<ref>PMID:17352535</ref>, '''OspC'''<ref>PMID:26438793</ref> and '''OspE'''<ref>PMID:8262642</ref> are major antigens on the surface of the Lyme disease spirochetes when it is being transmitted to humans. For more details see:<br /> | ||
OspA - <br /> | OspA - <br /> | ||
*[[G09SecL04Tpc2]]<br /> | *[[G09SecL04Tpc2]]<br /> | ||
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** [[4j38]] – OspE + complement factor H<br /> | ** [[4j38]] – OspE + complement factor H<br /> | ||
}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
