4zs8: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 4zs8 is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of ligand-free, full length DasR==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[4zs8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZS8 FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zs8 OCA], [http://pdbe.org/4zs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zs8 RCSB], [http://www.ebi.ac.uk/pdbsum/4zs8 PDBsum]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/DASR_STRCO DASR_STRCO]] Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis. Binds to the DNA consensus sequence 5'-ACTGGTCTAGACCACT-3'.<ref>PMID:15247334</ref> <ref>PMID:16925557</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Fillenberg, S B]]

[[Category: Muller, Y A]]

[[Category: Bacterial transcription regulation]]

[[Category: Gntr/hutc family]]

[[Category: Ligand-free]]

[[Category: Master regulator]]

[[Category: N-acetylglucosamine utilization]]

[[Category: Repressor]]

[[Category: Transcription]]

[[Category: Transcription factor]]

[[Category: Winged helix-turn-helix motif]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4zs8 is ON HOLD  until Paper Publication
+==Crystal structure of ligand-free, full length DasR==
+<StructureSection load='4zs8' size='340' side='right' caption='[[4zs8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4zs8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZS8 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zs8 OCA], [http://pdbe.org/4zs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zs8 RCSB], [http://www.ebi.ac.uk/pdbsum/4zs8 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DASR_STRCO DASR_STRCO]] Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N-acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin, as well as several genes involved in development, thereby linking carbon availability to morphogenesis. Binds to the DNA consensus sequence 5'-ACTGGTCTAGACCACT-3'.<ref>PMID:15247334</ref> <ref>PMID:16925557</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Fillenberg, S B]]
+[[Category: Muller, Y A]]
+[[Category: Bacterial transcription regulation]]
+[[Category: Gntr/hutc family]]
+[[Category: Ligand-free]]
+[[Category: Master regulator]]
+[[Category: N-acetylglucosamine utilization]]
+[[Category: Repressor]]
+[[Category: Transcription]]
+[[Category: Transcription factor]]
+[[Category: Winged helix-turn-helix motif]]