5buc: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5buc is ~~ON HOLD until Paper Publication~~

==Oxidized quinone reductase 2 in complex with ethidium==

~~Authors~~: ~~Leung~~, K.K., ~~Shilton~~, B.H.

== Structural highlights ==

<table><tr><td colspan='2'>[[5buc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BUC OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BUC FirstGlance].

~~Description~~: ~~Oxidized~~ quinone reductase 2 in ~~complex~~ with ~~ethidium~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ET:ETHIDIUM'>ET</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

~~[[Category: Unreleased Structures]]~~

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Ribosyldihydronicotinamide_dehydrogenase_(quinone) Ribosyldihydronicotinamide dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.99.2 1.10.99.2] </td></tr>

[[Category: Leung, K.K]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5buc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5buc OCA], [http://pdbe.org/5buc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5buc RCSB], [http://www.ebi.ac.uk/pdbsum/5buc PDBsum]</td></tr>

[[Category: Shilton, B.H]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Leung, K K]]

[[Category: Shilton, B H]]

[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

[[Category: Quinone reductase 2]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5buc is ON HOLD  until Paper Publication
+==Oxidized quinone reductase 2 in complex with ethidium==
+<StructureSection load='5buc' size='340' side='right' caption='[[5buc]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
-Authors: Leung, K.K., Shilton, B.H.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5buc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BUC FirstGlance]. <br>
-Description: Oxidized quinone reductase 2 in complex with ethidium
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ET:ETHIDIUM'>ET</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribosyldihydronicotinamide_dehydrogenase_(quinone) Ribosyldihydronicotinamide dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.10.99.2 1.10.99.2] </span></td></tr>
-[[Category: Leung, K.K]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5buc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5buc OCA], [http://pdbe.org/5buc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5buc RCSB], [http://www.ebi.ac.uk/pdbsum/5buc PDBsum]</span></td></tr>
-[[Category: Shilton, B.H]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN]] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Leung, K K]]
+[[Category: Shilton, B H]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Quinone reductase 2]]