Peroxiredoxin: Difference between revisions
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'''Typical 2-Cys Prx'''<br /> | '''Typical 2-Cys Prx'''<br /> | ||
* '''Prx 1''' interacts with signaling molecules<ref>PMID:19923889</ref>. | * '''Prx 1''' interacts with signaling molecules<ref>PMID:19923889</ref>. | ||
* '''Prx 2''' | * '''Prx 2''' is essential for sustaining erythrocyte life span<ref>PMID:18479207</ref>. | ||
* '''Prx 3''' | * '''Prx 3''' is mitochondria-specific.<ref>PMID:15280382</ref>. | ||
* '''Prx 4''' | * '''Prx 4''' localizes to the cytoplasm and regulates the activation of NF-κB<ref>PMID:25656995</ref>. | ||
'''Atypical 2-Cys Prx'''<br /> | '''Atypical 2-Cys Prx'''<br /> | ||
* '''Prx 5''' interacts with signaling molecules<ref>PMID:19923889</ref>. | * '''Prx 5''' interacts with signaling molecules<ref>PMID:19923889</ref>. | ||
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== Relevance == | == Relevance == | ||
Prx are over expressed in cancer tissue<ref>PMID:11497302</ref>. | Prx are over expressed in cancer tissue<ref>PMID:11497302</ref>. Prx 4 mediates osteoclast activation in cancer cells<ref>PMID:25779674</ref>. | ||
== 3D Structures of Peroxiredoxin == | == 3D Structures of Peroxiredoxin == | ||
