5iry: Difference between revisions
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==Crystal structure of human Desmocollin-1 ectodomain== | |||
<StructureSection load='5iry' size='340' side='right' caption='[[5iry]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5iry]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IRY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IRY FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iry OCA], [http://pdbe.org/5iry PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iry RCSB], [http://www.ebi.ac.uk/pdbsum/5iry PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DSC1_HUMAN DSC1_HUMAN]] Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Brasch, J]] | |||
[[Category: Harrison, O J]] | |||
[[Category: Shapiro, L]] | |||
[[Category: Cell adhesion]] | |||
[[Category: Cell surface]] | |||
[[Category: Desmosome]] | |||
[[Category: Extracellular cadherin domain]] | |||
Revision as of 23:28, 23 June 2016
Crystal structure of human Desmocollin-1 ectodomain
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