5jk9: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5jk9 is ~~ON HOLD until Paper Publication~~

==Crystal structure of human IZUMO1==

~~Authors~~: ~~Ohto~~, U., ~~Ishida~~, H., ~~Shimizu~~, T.

== Structural highlights ==

<table><tr><td colspan='2'>[[5jk9]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JK9 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JK9 FirstGlance].

~~Description: Crystal structure of human IZUMO1~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

~~[[Category: Shimizu, T]]~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jk9 OCA], [http://pdbe.org/5jk9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jk9 RCSB], [http://www.ebi.ac.uk/pdbsum/5jk9 PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/IZUM1_HUMAN IZUM1_HUMAN]] Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.<ref>PMID:15759005</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Ishida, H]]

[[Category: Ohto, U]]

[[Category: Shimizu, T]]

[[Category: Cell adhesion]]

[[Category: Fertilization]]

[[Category: Izumo1]]

[[Category: Juno]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5jk9 is ON HOLD  until Paper Publication
+==Crystal structure of human IZUMO1==
+<StructureSection load='5jk9' size='340' side='right' caption='[[5jk9]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-Authors: Ohto, U., Ishida, H., Shimizu, T.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5jk9]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JK9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JK9 FirstGlance]. <br>
-Description: Crystal structure of human IZUMO1
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jke|5jke]], [[5jkd|5jkd]], [[5jkc|5jkc]], [[5jkb|5jkb]], [[5jka|5jka]]</td></tr>
-[[Category: Shimizu, T]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jk9 OCA], [http://pdbe.org/5jk9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jk9 RCSB], [http://www.ebi.ac.uk/pdbsum/5jk9 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/IZUM1_HUMAN IZUM1_HUMAN]] Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.<ref>PMID:15759005</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Ishida, H]]
 [[Category: Ohto, U]]
+[[Category: Shimizu, T]]
+[[Category: Cell adhesion]]
+[[Category: Fertilization]]
+[[Category: Izumo1]]
+[[Category: Juno]]