5jkb: Difference between revisions
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==Crystal structure of human JUNO (crystal form 2)== | |||
<StructureSection load='5jkb' size='340' side='right' caption='[[5jkb]], [[Resolution|resolution]] 3.23Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5jkb]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JKB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JKB FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jke|5jke]], [[5jkd|5jkd]], [[5jkc|5jkc]], [[5jka|5jka]], [[5jk9|5jk9]]</td></tr> | ||
[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jkb OCA], [http://pdbe.org/5jkb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jkb RCSB], [http://www.ebi.ac.uk/pdbsum/5jkb PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/JUNO_HUMAN JUNO_HUMAN]] Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate.[UniProtKB:Q9EQF4] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ishida, H]] | [[Category: Ishida, H]] | ||
[[Category: Ohto, U]] | [[Category: Ohto, U]] | ||
[[Category: Shimizu, T]] | |||
[[Category: Cell adhesion]] | |||
[[Category: Fertilization]] | |||
[[Category: Izumo1]] | |||
[[Category: Juno]] | |||
Revision as of 23:29, 23 June 2016
Crystal structure of human JUNO (crystal form 2)
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