4ym9: Difference between revisions
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==Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102== | |||
<StructureSection load='4ym9' size='340' side='right' caption='[[4ym9]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ym9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YM9 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4E4:2-ETHYL-2-(HYDROXYMETHYL)-N-(6-METHYLPYRIDIN-3-YL)BUTANAMIDE'>4E4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ym9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ym9 OCA], [http://pdbe.org/4ym9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ym9 RCSB], [http://www.ebi.ac.uk/pdbsum/4ym9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ym9 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG]] Acts upon elastin. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Pancreatic elastase]] | |||
[[Category: Sus scrofa]] | |||
[[Category: Archer, M]] | |||
[[Category: Brito, J A]] | |||
[[Category: Hofbauer, S]] | |||
[[Category: Moreira, R]] | |||
[[Category: Mulchande, J]] | |||
[[Category: Nogly, P]] | [[Category: Nogly, P]] | ||
[[Category: Pessanha, M]] | [[Category: Pessanha, M]] | ||
[[Category: | [[Category: Hydrolase]] | ||
[[Category: | [[Category: Inhibitor]] | ||
[[Category: Porcine pancreatic elastase]] | |||
Revision as of 10:13, 13 July 2016
Crystal structure of Porcine Pancreatic Elastase (PPE) in complex with the novel inhibitor JM102
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