2na8: Difference between revisions
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==Transmembrane Structure of the Cytokine Receptor Common Subunit beta== | |||
<StructureSection load='2na8' size='340' side='right' caption='[[2na8]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2na8]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NA8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NA8 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2na8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2na8 OCA], [http://pdbe.org/2na8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2na8 RCSB], [http://www.ebi.ac.uk/pdbsum/2na8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2na8 ProSAT]</span></td></tr> | |||
[[ | </table> | ||
[[ | == Disease == | ||
[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: An, W]] | [[Category: An, W]] | ||
[[Category: | [[Category: Ginsberg, M H]] | ||
[[Category: Schmidt, T]] | [[Category: Schmidt, T]] | ||
[[Category: Situ, A J]] | |||
[[Category: Ulmer, T S]] | |||
[[Category: Ye, F]] | [[Category: Ye, F]] | ||
[[Category: | [[Category: Membrane protein]] | ||
[[Category: Transmembrane helix]] | |||
Revision as of 17:54, 13 July 2016
Transmembrane Structure of the Cytokine Receptor Common Subunit beta
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