5ce1: Difference between revisions
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==Crystal Structure of Serine protease Hepsin in complex with Inhibitor== | |||
<StructureSection load='5ce1' size='340' side='right' caption='[[5ce1]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ce1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CE1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CE1 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=50K:2-[6-(1-HYDROXYCYCLOHEXYL)PYRIDIN-2-YL]-1H-INDOLE-5-CARBOXIMIDAMIDE'>50K</scene></td></tr> | |||
[[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hepsin Hepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.106 3.4.21.106] </span></td></tr> | ||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ce1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ce1 OCA], [http://pdbe.org/5ce1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ce1 RCSB], [http://www.ebi.ac.uk/pdbsum/5ce1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ce1 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/HEPS_HUMAN HEPS_HUMAN]] Plays an essential role in cell growth and maintenance of cell morphology. May mediate the activating cleavage of HGF and MST1/HGFL.<ref>PMID:21875933</ref> <ref>PMID:15839837</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Hepsin]] | |||
[[Category: Anirudha, L]] | [[Category: Anirudha, L]] | ||
[[Category: Anita, R C]] | |||
[[Category: Rao, K N]] | |||
[[Category: Sangeetha, R]] | [[Category: Sangeetha, R]] | ||
[[Category: | [[Category: Subramnay, H]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | |||
[[Category: Prostate cancer]] | |||
[[Category: Serine protease]] | |||
Revision as of 17:57, 13 July 2016
Crystal Structure of Serine protease Hepsin in complex with Inhibitor
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