5l5g: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry 5l5g~~ is ~~ON HOLD~~

==Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5l5g]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L5G FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l5g OCA], [http://pdbe.org/5l5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l5g RCSB], [http://www.ebi.ac.uk/pdbsum/5l5g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l5g ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PLXA2_MOUSE PLXA2_MOUSE]] Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.<ref>PMID:10520994</ref> <ref>PMID:10781943</ref> <ref>PMID:20877282</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Coles, C H]]

[[Category: Gilbert, R J.C]]

[[Category: Janssen, B J.C]]

[[Category: Jones, E Y]]

[[Category: Kaufmann, R]]

[[Category: Kong, Y]]

[[Category: Malinauskas, T]]

[[Category: Ni, T]]

[[Category: Padilla-Parra, S]]

[[Category: Pasterkamp, R J]]

[[Category: Vangoor, V R]]

[[Category: Axon guidance]]

[[Category: Receptor]]

[[Category: Signaling]]

[[Category: Signaling protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5l5g is ON HOLD
+==Plexin A2 full extracellular region, domains 1 to 8 modeled, data to 10 angstrom==
+<StructureSection load='5l5g' size='340' side='right' caption='[[5l5g]], [[Resolution|resolution]] 10.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5l5g]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L5G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L5G FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l5g OCA], [http://pdbe.org/5l5g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l5g RCSB], [http://www.ebi.ac.uk/pdbsum/5l5g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l5g ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PLXA2_MOUSE PLXA2_MOUSE]] Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.<ref>PMID:10520994</ref> <ref>PMID:10781943</ref> <ref>PMID:20877282</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Coles, C H]]
+[[Category: Gilbert, R J.C]]
+[[Category: Janssen, B J.C]]
+[[Category: Jones, E Y]]
+[[Category: Kaufmann, R]]
+[[Category: Kong, Y]]
+[[Category: Malinauskas, T]]
+[[Category: Ni, T]]
+[[Category: Padilla-Parra, S]]
+[[Category: Pasterkamp, R J]]
+[[Category: Vangoor, V R]]
+[[Category: Axon guidance]]
+[[Category: Receptor]]
+[[Category: Signaling]]
+[[Category: Signaling protein]]