2mx2: Difference between revisions
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==UBX-L domain of VCIP135== | |||
<StructureSection load='2mx2' size='340' side='right' caption='[[2mx2]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2mx2]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MX2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MX2 FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ubiquitinyl_hydrolase_1 Ubiquitinyl hydrolase 1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.12 3.4.19.12] </span></td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mx2 OCA], [http://pdbe.org/2mx2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mx2 RCSB], [http://www.ebi.ac.uk/pdbsum/2mx2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mx2 ProSAT]</span></td></tr> | ||
</table> | |||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/VCIP1_RAT VCIP1_RAT]] Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP. Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.<ref>PMID:12473691</ref> <ref>PMID:15037600</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Ubiquitinyl hydrolase 1]] | |||
[[Category: Hrioaki, H]] | [[Category: Hrioaki, H]] | ||
[[Category: Igarashi, R]] | |||
[[Category: Iwazu, T]] | [[Category: Iwazu, T]] | ||
[[Category: Murayama, S]] | |||
[[Category: Shirakawa, M]] | |||
[[Category: Tochio, H]] | [[Category: Tochio, H]] | ||
[[Category: | [[Category: Golgi]] | ||
[[Category: Hydrolase]] | |||
[[Category: Mitosis]] | |||
[[Category: Ubx domain]] | |||
Revision as of 11:39, 14 July 2016
UBX-L domain of VCIP135
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