3jb8: Difference between revisions
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==Insight into Three-dimensional structure of Maize Chlorotic Mottle Virus Revealed by Single Particle Analysis== | |||
<StructureSection load='3jb8' size='340' side='right' caption='[[3jb8]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3jb8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Maize_chlorotic_mottle_virus Maize chlorotic mottle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JB8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JB8 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jb8 OCA], [http://pdbe.org/3jb8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jb8 RCSB], [http://www.ebi.ac.uk/pdbsum/3jb8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jb8 ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Maize chlorotic mottle virus (MCMV) is the only member of the Machlomovirus genus in the family Tombusviridae. Here, we obtained the Cryo-EM structure of MCMV by single particle analysis with most local resolution at approximately 4 A. The Calpha backbone was built based on residues with bulky side chains. The resolved C-terminus of the capsid protein subunit and obvious openings at the 2-fold axis demonstrated the compactness of the asymmetric unit, which indicates an important role in the stability of MCMV. The Asp116 residue from each subunit around the 5-fold and 3-fold axes contributed to the negative charges in the centers of the pentamers and hexamers, which might serve as a solid barrier against the leakage of genomic RNA. Finally, the loops most exposed on the surface were analyzed and are proposed to be potential functional sites related to MCMV transmission. | |||
Insight into the three-dimensional structure of maize chlorotic mottle virus revealed by Cryo-EM single particle analysis.,Wang CY, Zhang QF, Gao YZ, Zhou XP, Ji G, Huang XJ, Hong J, Zhang CX Virology. 2015 Nov;485:171-8. doi: 10.1016/j.virol.2015.07.014. Epub 2015 Aug 11. PMID:26275511<ref>PMID:26275511</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: | <div class="pdbe-citations 3jb8" style="background-color:#fffaf0;"></div> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Maize chlorotic mottle virus]] | |||
[[Category: Gao, Y Z]] | |||
[[Category: Hong, J]] | |||
[[Category: Huang, X J]] | |||
[[Category: Ji, G]] | [[Category: Ji, G]] | ||
[[Category: | [[Category: Wang, C Y]] | ||
[[Category: | [[Category: Zhang, C X]] | ||
[[Category: Zhang, | [[Category: Zhang, Q F]] | ||
[[Category: | [[Category: Zhou, X P]] | ||
[[Category: | [[Category: Icosahedral virus]] | ||
[[Category: Mcmv]] | |||
[[Category: Single particle analysis]] | |||
[[Category: Three-dimensional structure]] | |||
[[Category: Transmission]] | |||
[[Category: Virus]] | |||
Revision as of 11:39, 14 July 2016
Insight into Three-dimensional structure of Maize Chlorotic Mottle Virus Revealed by Single Particle Analysis
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