5l93: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==An atomic model of HIV-1 CA-SP1 reveals structures regulating assembly and maturation== | |||
<StructureSection load='5l93' size='340' side='right' caption='[[5l93]], [[Resolution|resolution]] 3.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5l93]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L93 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L93 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l93 OCA], [http://pdbe.org/5l93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l93 RCSB], [http://www.ebi.ac.uk/pdbsum/5l93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l93 ProSAT]</span></td></tr> | |||
</table> | |||
[[Category: | == Function == | ||
[[Category: | [[http://www.uniprot.org/uniprot/GAG_HV1N5 GAG_HV1N5]] Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu. Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers. p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1 (By similarity). | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Arjen, J J]] | ||
[[Category: Briggs, J A.G]] | |||
[[Category: Hagen, W J.H]] | |||
[[Category: Kirkpatrick, J M]] | |||
[[Category: Kraeusslich, H-G]] | |||
[[Category: Obr, M]] | [[Category: Obr, M]] | ||
[[Category: Sachse, C]] | [[Category: Sachse, C]] | ||
[[Category: Schur, F K.M]] | |||
[[Category: Wan, W]] | |||
[[Category: Hiv-1 capsid sp1]] | |||
[[Category: Viral protein]] | |||
Revision as of 11:51, 14 July 2016
An atomic model of HIV-1 CA-SP1 reveals structures regulating assembly and maturation
| ||||||||||||
