Sandbox 122: Difference between revisions
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<Structure load='4eyl' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene NDM1' /> | <Structure load='4eyl' size='350' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene NDM1' /> | ||
The NDM-1 is a metallo-protein and associated with the bacterial cell membrane. The active site contains key features for hydrolyzing carbapenems: | |||
- Zinc ion 1(Zn1) is coordinated by three histidine residues: H120, H122 and H189 | |||
- Zinc ion (Zn2) is coordinated by three residues: H250, C208 and D124 | |||