Sandbox 122: Difference between revisions
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The NDM-1 is a metallo-protein and associated with the bacterial cell membrane. The active site contains key features for hydrolyzing carbapenems: | The NDM-1 is a metallo-protein and associated with the bacterial cell membrane. The active site contains key features for hydrolyzing carbapenems: | ||
*Zinc ion 1(Zn1) is coordinated by three histidine residues: H120, H122 and H189 | |||
*Zinc ion (Zn2) is coordinated by three residues: H250, C208 and D124 | |||