4fa2: Difference between revisions
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==Human P38 alpha Mitogen-Activated Kinase In Complex With SB239063== | ==Human P38 alpha Mitogen-Activated Kinase In Complex With SB239063== | ||
<StructureSection load='4fa2' size='340' side='right' caption='[[4fa2]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4fa2' size='340' side='right' caption='[[4fa2]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4fa2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4fa2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FA2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FA2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GG5:4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE'>GG5</scene>, <scene name='pdbligand=SB0:TRANS-4-[4-(4-FLUOROPHENYL)-5-(2-METHOXYPYRIMIDIN-4-YL)-1H-IMIDAZOL-1-YL]CYCLOHEXANOL'>SB0</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GG5:4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE'>GG5</scene>, <scene name='pdbligand=SB0:TRANS-4-[4-(4-FLUOROPHENYL)-5-(2-METHOXYPYRIMIDIN-4-YL)-1H-IMIDAZOL-1-YL]CYCLOHEXANOL'>SB0</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ewq|4ewq]], [[4f9w|4f9w]], [[4f9y|4f9y]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ewq|4ewq]], [[4f9w|4f9w]], [[4f9y|4f9y]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fa2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fa2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fa2 RCSB], [http://www.ebi.ac.uk/pdbsum/4fa2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fa2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fa2 OCA], [http://pdbe.org/4fa2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fa2 RCSB], [http://www.ebi.ac.uk/pdbsum/4fa2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fa2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4fa2" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Mitogen-activated protein kinase]] | [[Category: Mitogen-activated protein kinase]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] | ||