3w32: Difference between revisions

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==EGFR kinase domain complexed with compound 20a==
==EGFR kinase domain complexed with compound 20a==
<StructureSection load='3w32' size='340' side='right' caption='[[3w32]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3w32' size='340' side='right' caption='[[3w32]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3w32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W32 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3w32]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W32 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=W32:4-({3-CHLORO-4-[3-(TRIFLUOROMETHYL)PHENOXY]PHENYL}AMINO)-N-[2-(METHYLSULFONYL)ETHYL]-8,9-DIHYDRO-7H-PYRIMIDO[4,5-B]AZEPINE-6-CARBOXAMIDE'>W32</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=W32:4-({3-CHLORO-4-[3-(TRIFLUOROMETHYL)PHENOXY]PHENYL}AMINO)-N-[2-(METHYLSULFONYL)ETHYL]-8,9-DIHYDRO-7H-PYRIMIDO[4,5-B]AZEPINE-6-CARBOXAMIDE'>W32</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3poz|3poz]], [[3w33|3w33]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3poz|3poz]], [[3w33|3w33]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EGFR, ERBB, ERBB1, HER1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EGFR, ERBB, ERBB1, HER1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w32 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w32 RCSB], [http://www.ebi.ac.uk/pdbsum/3w32 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w32 OCA], [http://pdbe.org/3w32 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w32 RCSB], [http://www.ebi.ac.uk/pdbsum/3w32 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w32 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3w32" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Kawakita, Y]]
[[Category: Kawakita, Y]]
Retrieved from "https://proteopedia.org/3w32"