4b0g: Difference between revisions

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==Complex of Aurora-A bound to an Imidazopyridine-based inhibitor==
==Complex of Aurora-A bound to an Imidazopyridine-based inhibitor==
<StructureSection load='4b0g' size='340' side='right' caption='[[4b0g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4b0g' size='340' side='right' caption='[[4b0g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4b0g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B0G FirstGlance]. <br>
<table><tr><td colspan='2'>[[4b0g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B0G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B0G FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VEK:6-BROMO-2-(1-METHYL-1H-IMIDAZOL-5-YL)-7-{4-[(5-METHYL-1,2-OXAZOL-3-YL)METHYL]PIPERAZIN-1-YL}-1H-IMIDAZO[4,5-B]PYRIDINE'>VEK</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=VEK:6-BROMO-2-(1-METHYL-1H-IMIDAZOL-5-YL)-7-{4-[(5-METHYL-1,2-OXAZOL-3-YL)METHYL]PIPERAZIN-1-YL}-1H-IMIDAZO[4,5-B]PYRIDINE'>VEK</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mq4|1mq4]], [[1muo|1muo]], [[1ol5|1ol5]], [[1ol6|1ol6]], [[1ol7|1ol7]], [[2bmc|2bmc]], [[2c6d|2c6d]], [[2c6e|2c6e]], [[2j4z|2j4z]], [[2j50|2j50]], [[2w1c|2w1c]], [[2w1d|2w1d]], [[2w1e|2w1e]], [[2w1f|2w1f]], [[2w1g|2w1g]], [[2wqe|2wqe]], [[2wtv|2wtv]], [[2wtw|2wtw]], [[2x6d|2x6d]], [[2x6e|2x6e]], [[2x81|2x81]], [[2xne|2xne]], [[2xng|2xng]], [[2xru|2xru]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mq4|1mq4]], [[1muo|1muo]], [[1ol5|1ol5]], [[1ol6|1ol6]], [[1ol7|1ol7]], [[2bmc|2bmc]], [[2c6d|2c6d]], [[2c6e|2c6e]], [[2j4z|2j4z]], [[2j50|2j50]], [[2w1c|2w1c]], [[2w1d|2w1d]], [[2w1e|2w1e]], [[2w1f|2w1f]], [[2w1g|2w1g]], [[2wqe|2wqe]], [[2wtv|2wtv]], [[2wtw|2wtw]], [[2x6d|2x6d]], [[2x6e|2x6e]], [[2x81|2x81]], [[2xne|2xne]], [[2xng|2xng]], [[2xru|2xru]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b0g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b0g RCSB], [http://www.ebi.ac.uk/pdbsum/4b0g PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b0g OCA], [http://pdbe.org/4b0g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b0g RCSB], [http://www.ebi.ac.uk/pdbsum/4b0g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b0g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4b0g" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Bayliss, R]]
[[Category: Bayliss, R]]
Retrieved from "https://proteopedia.org/4b0g"