2yit: Difference between revisions
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==STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH PV1162, A NOVEL INHIBITOR== | ==STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH PV1162, A NOVEL INHIBITOR== | ||
<StructureSection load='2yit' size='340' side='right' caption='[[2yit]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2yit' size='340' side='right' caption='[[2yit]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yit]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2yit]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YIT FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=YIT:N-{4-[(1E)-N-CARBAMIMIDOYLBUTANEHYDRAZONOYL]PHENYL}-5-METHOXY-1H-INDOLE-2-CARBOXAMIDE'>YIT</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=YIT:N-{4-[(1E)-N-CARBAMIMIDOYLBUTANEHYDRAZONOYL]PHENYL}-5-METHOXY-1H-INDOLE-2-CARBOXAMIDE'>YIT</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2cn8|2cn8]], [[2w0j|2w0j]], [[2ycf|2ycf]], [[2yir|2yir]], [[2wtc|2wtc]], [[2ycr|2ycr]], [[2ycq|2ycq]], [[1gxc|1gxc]], [[2wtd|2wtd]], [[2xbj|2xbj]], [[2ycs|2ycs]], [[2wtj|2wtj]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[2yiq|2yiq]], [[2cn5|2cn5]], [[2xm8|2xm8]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2cn8|2cn8]], [[2w0j|2w0j]], [[2ycf|2ycf]], [[2yir|2yir]], [[2wtc|2wtc]], [[2ycr|2ycr]], [[2ycq|2ycq]], [[1gxc|1gxc]], [[2wtd|2wtd]], [[2xbj|2xbj]], [[2ycs|2ycs]], [[2wtj|2wtj]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[2yiq|2yiq]], [[2cn5|2cn5]], [[2xm8|2xm8]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yit OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yit RCSB], [http://www.ebi.ac.uk/pdbsum/2yit PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yit OCA], [http://pdbe.org/2yit PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yit RCSB], [http://www.ebi.ac.uk/pdbsum/2yit PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yit ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2yit" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Jobson, A G]] | [[Category: Jobson, A G]] | ||
