3t1a: Difference between revisions
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==Crystal Structure of HIV-1 Reverse Transcriptase (K103N mutant) in Complex with Inhibitor M05== | ==Crystal Structure of HIV-1 Reverse Transcriptase (K103N mutant) in Complex with Inhibitor M05== | ||
<StructureSection load='3t1a' size='340' side='right' caption='[[3t1a]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='3t1a' size='340' side='right' caption='[[3t1a]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3t1a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv- | <table><tr><td colspan='2'>[[3t1a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T1A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T1A FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5MA:1-(2,5-DICHLORO-3-{[5-CHLORO-1-(2H-PYRAZOLO[3,4-B]PYRIDIN-3-YLMETHYL)-1H-BENZOTRIAZOL-4-YL]OXY}PHENYL)METHANAMINE'>5MA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5MA:1-(2,5-DICHLORO-3-{[5-CHLORO-1-(2H-PYRAZOLO[3,4-B]PYRIDIN-3-YLMETHYL)-1H-BENZOTRIAZOL-4-YL]OXY}PHENYL)METHANAMINE'>5MA</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t19|3t19]], [[3tam|3tam]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t19|3t19]], [[3tam|3tam]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, HIV-1 POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, HIV-1 POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t1a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t1a RCSB], [http://www.ebi.ac.uk/pdbsum/3t1a PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t1a OCA], [http://pdbe.org/3t1a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t1a RCSB], [http://www.ebi.ac.uk/pdbsum/3t1a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t1a ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3t1a" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hiv-1 | [[Category: Hiv-1]] | ||
[[Category: Reid, J]] | [[Category: Reid, J]] | ||
[[Category: Yan, Y]] | [[Category: Yan, Y]] | ||
[[Category: Hiv-1 reverse transcriptase]] | [[Category: Hiv-1 reverse transcriptase]] | ||
[[Category: Non-nucleoside inhibition]] | [[Category: Non-nucleoside inhibition]] | ||
