Sandbox 130: Difference between revisions

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'''How does Kapβ2 identify its cargo?'''
'''How does Kapβ2 identify its cargo?'''
The NLS located on Kapβ2 cargos are named the PY-NLS and they bind to the C-terminal arch of Kapβ2. The electrostatic potential of the internal surface of Kapβ2 superhelix at the C-terminal arch is negative.
The NLS located on Kapβ2 cargos are named the PY-NLS and they bind to the C-terminal arch of Kapβ2. The electrostatic potential of the internal surface of Kapβ2 superhelix at the C-terminal arch is negative.
Recognition of the PY-NLS by Kapβ2 fallows certain guidelines:
Recognition of the PY-NLS by Kapβ2 fallows certain guidelines:
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