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==Crystal structure of mutant E.coli topoisomerase IA==
==Crystal structure of mutant E.coli topoisomerase IA==
<StructureSection load='3pwt' size='340' side='right' caption='[[3pwt]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3pwt' size='340' side='right' caption='[[3pwt]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3pwt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PWT FirstGlance]. <br>
<table><tr><td colspan='2'>[[3pwt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PWT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ecl|1ecl]], [[1cy0|1cy0]], [[1cy2|1cy2]], [[1cy4|1cy4]], [[1cy6|1cy6]], [[1cy7|1cy7]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ecl|1ecl]], [[1cy0|1cy0]], [[1cy2|1cy2]], [[1cy4|1cy4]], [[1cy6|1cy6]], [[1cy7|1cy7]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">topA, supX, b1274, JW1266 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">topA, supX, b1274, JW1266 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pwt RCSB], [http://www.ebi.ac.uk/pdbsum/3pwt PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pwt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwt OCA], [http://pdbe.org/3pwt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pwt RCSB], [http://www.ebi.ac.uk/pdbsum/3pwt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</StructureSection>
</StructureSection>
[[Category: DNA topoisomerase]]
[[Category: DNA topoisomerase]]
[[Category: Escherichia coli]]
[[Category: Ecoli]]
[[Category: Bokun, C]]
[[Category: Bokun, C]]
[[Category: Tse-Dinh, Y C]]
[[Category: Tse-Dinh, Y C]]

Revision as of 00:04, 5 August 2016

Crystal structure of mutant E.coli topoisomerase IA

3pwt, resolution 1.90Å

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