2xx7: Difference between revisions

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==CRYSTAL STRUCTURE OF 1-(4-(1-PYRROLIDINYLCARBONYL)PHENYL)-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 2.2A RESOLUTION.==
==CRYSTAL STRUCTURE OF 1-(4-(1-PYRROLIDINYLCARBONYL)PHENYL)-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE IN COMPLEX WITH THE LIGAND BINDING DOMAIN OF THE RAT GLUA2 RECEPTOR AND GLUTAMATE AT 2.2A RESOLUTION.==
<StructureSection load='2xx7' size='340' side='right' caption='[[2xx7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2xx7' size='340' side='right' caption='[[2xx7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xx7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XX7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2xx7]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XX7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1ND:1-[4-(1-PYRROLIDINYLCARBONYL)PHENYL]-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE'>1ND</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1ND:1-[4-(1-PYRROLIDINYLCARBONYL)PHENYL]-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOLE'>1ND</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m5c|1m5c]], [[1p1o|1p1o]], [[1mqh|1mqh]], [[1lb8|1lb8]], [[1p1u|1p1u]], [[1mm7|1mm7]], [[1nnp|1nnp]], [[1m5d|1m5d]], [[1p1q|1p1q]], [[1syi|1syi]], [[1mqd|1mqd]], [[2i3v|2i3v]], [[2i3w|2i3w]], [[1p1w|1p1w]], [[1my4|1my4]], [[1mxu|1mxu]], [[1n0t|1n0t]], [[2xxi|2xxi]], [[1mqi|1mqi]], [[1ftk|1ftk]], [[2anj|2anj]], [[1fto|1fto]], [[1my3|1my3]], [[1mxv|1mxv]], [[1p1n|1p1n]], [[2xx9|2xx9]], [[1syh|1syh]], [[1ftj|1ftj]], [[1lbb|1lbb]], [[1fw0|1fw0]], [[1m5e|1m5e]], [[1mxz|1mxz]], [[1mxy|1mxy]], [[2xx8|2xx8]], [[1mqg|1mqg]], [[2aix|2aix]], [[1m5b|1m5b]], [[1mxw|1mxw]], [[1ms7|1ms7]], [[1my0|1my0]], [[2xxh|2xxh]], [[1m5f|1m5f]], [[1xhy|1xhy]], [[1my1|1my1]], [[2cmo|2cmo]], [[1mm6|1mm6]], [[2al4|2al4]], [[1mxx|1mxx]], [[1ftl|1ftl]], [[2uxa|2uxa]], [[1wvj|1wvj]], [[1ftm|1ftm]], [[1lb9|1lb9]], [[1lbc|1lbc]], [[1nnk|1nnk]], [[1my2|1my2]], [[1mqj|1mqj]], [[2al5|2al5]], [[1gr2|1gr2]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1m5c|1m5c]], [[1p1o|1p1o]], [[1mqh|1mqh]], [[1lb8|1lb8]], [[1p1u|1p1u]], [[1mm7|1mm7]], [[1nnp|1nnp]], [[1m5d|1m5d]], [[1p1q|1p1q]], [[1syi|1syi]], [[1mqd|1mqd]], [[2i3v|2i3v]], [[2i3w|2i3w]], [[1p1w|1p1w]], [[1my4|1my4]], [[1mxu|1mxu]], [[1n0t|1n0t]], [[2xxi|2xxi]], [[1mqi|1mqi]], [[1ftk|1ftk]], [[2anj|2anj]], [[1fto|1fto]], [[1my3|1my3]], [[1mxv|1mxv]], [[1p1n|1p1n]], [[2xx9|2xx9]], [[1syh|1syh]], [[1ftj|1ftj]], [[1lbb|1lbb]], [[1fw0|1fw0]], [[1m5e|1m5e]], [[1mxz|1mxz]], [[1mxy|1mxy]], [[2xx8|2xx8]], [[1mqg|1mqg]], [[2aix|2aix]], [[1m5b|1m5b]], [[1mxw|1mxw]], [[1ms7|1ms7]], [[1my0|1my0]], [[2xxh|2xxh]], [[1m5f|1m5f]], [[1xhy|1xhy]], [[1my1|1my1]], [[2cmo|2cmo]], [[1mm6|1mm6]], [[2al4|2al4]], [[1mxx|1mxx]], [[1ftl|1ftl]], [[2uxa|2uxa]], [[1wvj|1wvj]], [[1ftm|1ftm]], [[1lb9|1lb9]], [[1lbc|1lbc]], [[1nnk|1nnk]], [[1my2|1my2]], [[1mqj|1mqj]], [[2al5|2al5]], [[1gr2|1gr2]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xx7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2xx7 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xx7 OCA], [http://pdbe.org/2xx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xx7 RCSB], [http://www.ebi.ac.uk/pdbsum/2xx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xx7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2xx7" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Buffalo rat]]
[[Category: Aldegheri, L]]
[[Category: Aldegheri, L]]
[[Category: Austin, N E]]
[[Category: Austin, N E]]
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