4b6e: Difference between revisions
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==Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function== | ==Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function== | ||
<StructureSection load='4b6e' size='340' side='right' caption='[[4b6e]], [[Resolution|resolution]] 2.46Å' scene=''> | <StructureSection load='4b6e' size='340' side='right' caption='[[4b6e]], [[Resolution|resolution]] 2.46Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4b6e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4b6e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hcv Hcv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B6E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B6E FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=10L:1H-INDAZOL-7-AMINE'>10L</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=10L:1H-INDAZOL-7-AMINE'>10L</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a1q|1a1q]], [[1bt7|1bt7]], [[1c2p|1c2p]], [[1csj|1csj]], [[1cu1|1cu1]], [[1gx5|1gx5]], [[1gx6|1gx6]], [[1jxp|1jxp]], [[1nhu|1nhu]], [[1nhv|1nhv]], [[1ns3|1ns3]], [[1os5|1os5]], [[1quv|1quv]], [[2awz|2awz]], [[2ax0|2ax0]], [[2ax1|2ax1]], [[2brk|2brk]], [[2brl|2brl]], [[2i1r|2i1r]], [[2jc0|2jc0]], [[2jc1|2jc1]], [[2wcx|2wcx]], [[2who|2who]], [[2xwy|2xwy]], [[4a92|4a92]], [[8ohm|8ohm]], [[4b6f|4b6f]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a1q|1a1q]], [[1bt7|1bt7]], [[1c2p|1c2p]], [[1csj|1csj]], [[1cu1|1cu1]], [[1gx5|1gx5]], [[1gx6|1gx6]], [[1jxp|1jxp]], [[1nhu|1nhu]], [[1nhv|1nhv]], [[1ns3|1ns3]], [[1os5|1os5]], [[1quv|1quv]], [[2awz|2awz]], [[2ax0|2ax0]], [[2ax1|2ax1]], [[2brk|2brk]], [[2brl|2brl]], [[2i1r|2i1r]], [[2jc0|2jc0]], [[2jc1|2jc1]], [[2wcx|2wcx]], [[2who|2who]], [[2xwy|2xwy]], [[4a92|4a92]], [[8ohm|8ohm]], [[4b6f|4b6f]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b6e RCSB], [http://www.ebi.ac.uk/pdbsum/4b6e PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b6e OCA], [http://pdbe.org/4b6e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b6e RCSB], [http://www.ebi.ac.uk/pdbsum/4b6e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b6e ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4b6e" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hcv]] | |||
[[Category: Carr, M G]] | [[Category: Carr, M G]] | ||
[[Category: Chessari, G]] | [[Category: Chessari, G]] | ||
