3u9n: Difference between revisions
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==X-ray crystal structure of compound 1 bound to human CHK1 kinase domain== | ==X-ray crystal structure of compound 1 bound to human CHK1 kinase domain== | ||
<StructureSection load='3u9n' size='340' side='right' caption='[[3u9n]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='3u9n' size='340' side='right' caption='[[3u9n]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3u9n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3u9n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U9N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U9N FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=09H:2-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)-N-[2-(PIPERAZIN-1-YL)PHENYL]-1,3-THIAZOLE-4-CARBOXAMIDE'>09H</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=09H:2-(2,3-DIHYDRO-1-BENZOFURAN-5-YL)-N-[2-(PIPERAZIN-1-YL)PHENYL]-1,3-THIAZOLE-4-CARBOXAMIDE'>09H</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pa3|3pa3]], [[3pa4|3pa4]], [[3pa5|3pa5]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pa3|3pa3]], [[3pa4|3pa4]], [[3pa5|3pa5]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHEK1, CHK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHEK1, CHK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u9n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u9n RCSB], [http://www.ebi.ac.uk/pdbsum/3u9n PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u9n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u9n OCA], [http://pdbe.org/3u9n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u9n RCSB], [http://www.ebi.ac.uk/pdbsum/3u9n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u9n ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Fischmann, T O]] | [[Category: Fischmann, T O]] | ||