4ff8: Difference between revisions

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==Inhibitor bound structure of the kinase domain of the murine receptor tyrosine kinase TYRO3 (Sky)==
==Inhibitor bound structure of the kinase domain of the murine receptor tyrosine kinase TYRO3 (Sky)==
<StructureSection load='4ff8' size='340' side='right' caption='[[4ff8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4ff8' size='340' side='right' caption='[[4ff8]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ff8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FF8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ff8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FF8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=14S:4-(CYCLOPENTYLAMINO)-2-[(2-METHOXYBENZYL)AMINO]-N-[3-(2-OXOPYRROLIDIN-1-YL)PROPYL]PYRIMIDINE-5-CARBOXAMIDE'>14S</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=14S:4-(CYCLOPENTYLAMINO)-2-[(2-METHOXYBENZYL)AMINO]-N-[3-(2-OXOPYRROLIDIN-1-YL)PROPYL]PYRIMIDINE-5-CARBOXAMIDE'>14S</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qup|3qup]], [[4feq|4feq]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qup|3qup]], [[4feq|4feq]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tyro3, Dtk, Rse ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tyro3, Dtk, Rse ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ff8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ff8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ff8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ff8 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ff8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ff8 OCA], [http://pdbe.org/4ff8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ff8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ff8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ff8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4ff8" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Mus musculus]]
[[Category: Lk3 transgenic mice]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Kohrt, J]]
[[Category: Kohrt, J]]
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