Retinol-binding protein: Difference between revisions
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{{STRUCTURE_2rct| PDB=2rct | SIZE=400| SCENE= |right|CAPTION=Human cellular retinol-binding protein II complex with retinol, sulfate and tartarate, [[2rct]] }} | {{STRUCTURE_2rct| PDB=2rct | SIZE=400| SCENE= |right|CAPTION=Human cellular retinol-binding protein II complex with retinol, sulfate and tartarate, [[2rct]] }} | ||
== Function == | |||
'''Retinol-binding protein''' (RBP) are carrier proteins which bind retinol (vitamin A alcohol). Human RBP4 is the carrier of retinol in the blood. It delivers retinol from the liver to the peripheral tissues. RBP also functions in regulation, metabolism and activities of retinoids. Retinol is being protected from oxidation and becomes soluble when bound to RBP. RBP is classified according to its site of activity. '''Plasma RBP''' (PRBP) carries retinol in blood<ref>PMID:6994566</ref> while '''cellular RBP''' (CRBP) carries retinol in the cell<ref>PMID:2825608</ref>. | |||
== Relevance == | |||
RBP is used to assess vitamin A deficiency as it binds 1:1 to retinol. | |||
'''Retinol-binding protein''' (RBP) are carrier proteins which bind retinol (vitamin A alcohol). Human RBP4 is the carrier of retinol in the blood. It delivers retinol from the liver to the peripheral tissues. RBP also functions in regulation, metabolism and activities of retinoids. Retinol is being protected from oxidation and becomes soluble when bound to RBP | |||
==3D structures of retinol-binding protein== | ==3D structures of retinol-binding protein== | ||
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**[[1crb]], [[1opb]] - rRBP + retinol<br /> | **[[1crb]], [[1opb]] - rRBP + retinol<br /> | ||
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== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
