5exj: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5exj is ~~ON HOLD until Paper Publication~~

==Crystal structure of M. tuberculosis lipoyl synthase at 1.64 A resolution==

~~Authors~~: ~~McLaughlin~~, M.I., ~~Lanz, N~~.D., ~~Goldman, P~~.J., ~~Lee~~, K.-H., ~~Booker, S~~.J., ~~Drennan, C~~.L.

== Structural highlights ==

<table><tr><td colspan='2'>[[5exj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EXJ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EXJ FirstGlance].

~~Description~~: ~~Crystal structure~~ of ~~M. tuberculosis~~ lipoyl ~~synthase at 1~~.~~64 A resolution~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=DTV:(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL'>DTV</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5exi|5exi]], [[5exk|5exk]]</td></tr>

[[Category: ~~Goldman~~, P.J]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Lipoyl_synthase Lipoyl synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.8 2.8.1.8] </td></tr>

[[Category: ~~Mclaughlin~~, ~~M.I~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5exj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5exj OCA], [http://pdbe.org/5exj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5exj RCSB], [http://www.ebi.ac.uk/pdbsum/5exj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5exj ProSAT]</td></tr>

[[Category: Lanz, N.D]]

</table>

[[Category: ~~Drennan~~, ~~C.L~~]]

== Function ==

[[Category: ~~Booker~~, ~~S.J~~]]

[[http://www.uniprot.org/uniprot/LIPA_MYCTU LIPA_MYCTU]] Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.

[[Category: ~~Lee, K.~~-H]]

__TOC__

</StructureSection>

[[Category: Lipoyl synthase]]

[[Category: Booker, S J]]

[[Category: Drennan, C L]]

[[Category: Goldman, P J]]

[[Category: Lanz, N D]]

[[Category: Lee, K H]]

[[Category: McLaughlin, M I]]

[[Category: Adomet radical]]

[[Category: Auxiliary iron-sulfur cluster]]

[[Category: Radical sam]]

[[Category: Sulfur insertion]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5exj is ON HOLD  until Paper Publication
+==Crystal structure of M. tuberculosis lipoyl synthase at 1.64 A resolution==
+<StructureSection load='5exj' size='340' side='right' caption='[[5exj]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
-Authors: McLaughlin, M.I., Lanz, N.D., Goldman, P.J., Lee, K.-H., Booker, S.J., Drennan, C.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5exj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EXJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EXJ FirstGlance]. <br>
-Description: Crystal structure of M. tuberculosis lipoyl synthase at 1.64 A resolution
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTV:(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL'>DTV</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5exi|5exi]], [[5exk|5exk]]</td></tr>
-[[Category: Goldman, P.J]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lipoyl_synthase Lipoyl synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.8 2.8.1.8] </span></td></tr>
-[[Category: Mclaughlin, M.I]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5exj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5exj OCA], [http://pdbe.org/5exj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5exj RCSB], [http://www.ebi.ac.uk/pdbsum/5exj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5exj ProSAT]</span></td></tr>
-[[Category: Lanz, N.D]]
+</table>
-[[Category: Drennan, C.L]]
+== Function ==
-[[Category: Booker, S.J]]
+[[http://www.uniprot.org/uniprot/LIPA_MYCTU LIPA_MYCTU]] Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
-[[Category: Lee, K.-H]]
+__TOC__
+</StructureSection>
+[[Category: Lipoyl synthase]]
+[[Category: Booker, S J]]
+[[Category: Drennan, C L]]
+[[Category: Goldman, P J]]
+[[Category: Lanz, N D]]
+[[Category: Lee, K H]]
+[[Category: McLaughlin, M I]]
+[[Category: Adomet radical]]
+[[Category: Auxiliary iron-sulfur cluster]]
+[[Category: Radical sam]]
+[[Category: Sulfur insertion]]
+[[Category: Transferase]]