5kbd: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5kbd is ON HOLD~~

==Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element==

~~Authors: Nguyen, H.T., Huang, D.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5kbd]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KBD OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KBD FirstGlance].

~~Description:~~ Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5kd3|5kd3]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kbd OCA], [http://pdbe.org/5kbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kbd RCSB], [http://www.ebi.ac.uk/pdbsum/5kbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kbd ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Huang, D]]

[[Category: Nguyen, H.T]]

[[Category: Nguyen, H T]]

[[Category: Dna binding protein-dna complex]]

[[Category: Tumor suppressor transcription factor p53 response element]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5kbd is ON HOLD
+==Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element==
+<StructureSection load='5kbd' size='340' side='right' caption='[[5kbd]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors: Nguyen, H.T., Huang, D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5kbd]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KBD FirstGlance]. <br>
-Description: Structural Studies of Transcription Factor p73 DNA Binding Domain Bound to PA26 20-mer Response Element
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kd3|5kd3]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kbd OCA], [http://pdbe.org/5kbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kbd RCSB], [http://www.ebi.ac.uk/pdbsum/5kbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kbd ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Huang, D]]
-[[Category: Nguyen, H.T]]
+[[Category: Nguyen, H T]]
+[[Category: Dna binding protein-dna complex]]
+[[Category: Tumor suppressor transcription factor p53 response element]]