5kg8: Difference between revisions
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==Rigor myosin X co-complexed with an actin filament== | |||
<StructureSection load='5kg8' size='340' side='right' caption='[[5kg8]], [[Resolution|resolution]] 9.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5kg8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KG8 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kg8 OCA], [http://pdbe.org/5kg8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kg8 RCSB], [http://www.ebi.ac.uk/pdbsum/5kg8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kg8 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/MYO10_HUMAN MYO10_HUMAN]] Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podosome belt in osteoclasts (By similarity).<ref>PMID:16894163</ref> [[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Oryctolagus cuniculus]] | |||
[[Category: Houdusse, A]] | [[Category: Houdusse, A]] | ||
[[Category: Sindelar, C | [[Category: Sindelar, C V]] | ||
[[Category: Sweeney, L]] | [[Category: Sweeney, L]] | ||
[[Category: Motor protein]] | |||
[[Category: Myosin molecular motors cytoskeletal motility]] | |||
Revision as of 21:11, 10 September 2016
Rigor myosin X co-complexed with an actin filament
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