Thiolase: Difference between revisions

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{{STRUCTURE_2iik|  PDB=2iik  | SIZE=400| SCENE=Thiolase/Thiolase/2 |right|CAPTION=Human 3-ketoacyl-CoA thiolase dimer, [[2iik]] }}
{{STRUCTURE_2iik|  PDB=2iik  | SIZE=400| SCENE=Thiolase/Thiolase/2 |right|CAPTION=Human 3-ketoacyl-CoA thiolase dimer, [[2iik]] }}


Two different classes of '''thiolases''' are found . Degrative thiolase like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation. Biosynthetic thiolases like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA.
Two different classes of '''thiolases''' are found.<br />
*'''Degrative thiolase''' like '''3-ketoacyl-CoA thiolase''' (KCT) is involved in fatty acid β oxidation<ref>PMID:16630629</ref><.<br />
*'''Biosynthetic thiolases''' like '''acetoacetyl-CoA thiolase''' (ACT) are involved in the thiolysis of acetoacetyl-CoA<ref>PMID:21908473</ref><.


For Bacterial Thiolase see [[Bacterial thiolase]]
For Bacterial thiolase see [[Bacterial thiolase]]


== 3D Structures of Thiolase ==
== 3D Structures of Thiolase ==
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**[[4dd5]], [[4e1l]] – ACT – ''Clostridium difficile''<br />
**[[4dd5]], [[4e1l]] – ACT – ''Clostridium difficile''<br />
}}
}}
 
== References ==
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]