5e0z: Difference between revisions
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==Crystal Structure of PASTA Domains 3 and 4 of Mycobacterium tuberculosis Protein Kinase B== | |||
<StructureSection load='5e0z' size='340' side='right' caption='[[5e0z]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5e0z]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E0Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E0Z FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ouv|3ouv]], [[5e0y|5e0y]], [[5e10|5e10]], [[5e12|5e12]]</td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e0z OCA], [http://pdbe.org/5e0z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e0z RCSB], [http://www.ebi.ac.uk/pdbsum/5e0z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e0z ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PKNB_MYCTU PKNB_MYCTU]] Key component of a signal transduction pathway that regulates cell growth and cell division via phosphorylation of target proteins such as GarA, GlmU, PapA5, PbpA, FhaB (Rv0019c), FhaA (Rv0020c), MviN, PstP, EmbR, Rv1422, Rv1747 and RseA. Shows a strong preference for Thr versus Ser as the phosphoacceptor.<ref>PMID:15985609</ref> <ref>PMID:15978616</ref> <ref>PMID:15987910</ref> <ref>PMID:16817899</ref> <ref>PMID:16980473</ref> <ref>PMID:16436437</ref> <ref>PMID:19826007</ref> <ref>PMID:19121323</ref> <ref>PMID:20025669</ref> <ref>PMID:21423706</ref> <ref>PMID:22275220</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Non-specific serine/threonine protein kinase]] | |||
[[Category: Prigozhin, D M]] | |||
[[Category: Structural genomic]] | |||
[[Category: Extracellular sensor domain]] | |||
[[Category: Kinase]] | |||
[[Category: Peptidoglycan binding]] | |||
[[Category: Tbsgc]] | |||
[[Category: Transferase]] | |||