5gio: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5gio is ~~ON HOLD until Paper Publication~~

==Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5gio]] is a 15 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIO OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GIO FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5gip|5gip]], [[5gin|5gin]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gio OCA], [http://pdbe.org/5gio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gio RCSB], [http://www.ebi.ac.uk/pdbsum/5gio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gio ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/A0A0E3JUC9_SULSF A0A0E3JUC9_SULSF]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.[HAMAP-Rule:MF_00351] [[http://www.uniprot.org/uniprot/A0A0E3JZF7_SULSF A0A0E3JZF7_SULSF]] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.[HAMAP-Rule:MF_00326]

__TOC__

</StructureSection>

[[Category: Lin, J]]

[[Category: Yang, Z]]

[[Category: Ye, K]]

[[Category: 2'-o-methylation]]

[[Category: Guide rna]]

[[Category: Rnp]]

[[Category: Transferase-rna complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5gio is ON HOLD  until Paper Publication
+==Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates==
+<StructureSection load='5gio' size='340' side='right' caption='[[5gio]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5gio]] is a 15 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GIO FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gip|5gip]], [[5gin|5gin]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gio OCA], [http://pdbe.org/5gio PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gio RCSB], [http://www.ebi.ac.uk/pdbsum/5gio PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gio ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/A0A0E3JUC9_SULSF A0A0E3JUC9_SULSF]] Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.[HAMAP-Rule:MF_00351] [[http://www.uniprot.org/uniprot/A0A0E3JZF7_SULSF A0A0E3JZF7_SULSF]] Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.[HAMAP-Rule:MF_00326]
+__TOC__
+</StructureSection>
+[[Category: Lin, J]]
+[[Category: Yang, Z]]
+[[Category: Ye, K]]
+[[Category: 2'-o-methylation]]
+[[Category: Guide rna]]
+[[Category: Rnp]]
+[[Category: Transferase-rna complex]]