5t1i: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5t1i is ~~ON HOLD~~

==CBX3 chromo shadow domain in complex with histone H3 peptide==

~~Authors~~: ~~Liu~~, Y., ~~Tempel~~, W., ~~Bountra~~, C., ~~Weigelt, J~~.~~, Arrowsmith, C~~.H.~~, Edwards, A~~.M., ~~Min, J~~.~~, Structural Genomics Consortium~~ (~~SGC~~)

== Structural highlights ==

<table><tr><td colspan='2'>[[5t1i]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T1I OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T1I FirstGlance].

~~Description~~: ~~CBX3 chromo shadow domain in complex with histone H3 peptide~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=AAR:ARGININEAMIDE'>AAR</scene>, <scene name='pdbligand=N7P:1-ACETYL-L-PROLINE'>N7P</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5t1g|5t1g]]</td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t1i OCA], [http://pdbe.org/5t1i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t1i RCSB], [http://www.ebi.ac.uk/pdbsum/5t1i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t1i ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CBX3_HUMAN CBX3_HUMAN]] Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

__TOC__

</StructureSection>

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C]]

[[Category: Edwards, A M]]

[[Category: Liu, Y]]

[[Category: Min, J]]

[[Category: ~~Liu, Y]]~~

[[Category: Structural genomic]]

~~[[Category: Bountra, C~~]]

[[Category: Tempel, W]]

~~[[Category: Arrowsmith, C.H]]~~

~~[[Category: Edwards, A.M]]~~

~~[[Category: Structural Genomics Consortium (Sgc)]]~~

[[Category: Weigelt, J]]

[[Category: Sgc]]

[[Category: Transcription]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5t1i is ON HOLD
+==CBX3 chromo shadow domain in complex with histone H3 peptide==
+<StructureSection load='5t1i' size='340' side='right' caption='[[5t1i]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-Authors: Liu, Y., Tempel, W., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5t1i]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T1I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T1I FirstGlance]. <br>
-Description: CBX3 chromo shadow domain in complex with histone H3 peptide
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AAR:ARGININEAMIDE'>AAR</scene>, <scene name='pdbligand=N7P:1-ACETYL-L-PROLINE'>N7P</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5t1g|5t1g]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t1i OCA], [http://pdbe.org/5t1i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t1i RCSB], [http://www.ebi.ac.uk/pdbsum/5t1i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t1i ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CBX3_HUMAN CBX3_HUMAN]] Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
+__TOC__
+</StructureSection>
+[[Category: Arrowsmith, C H]]
+[[Category: Bountra, C]]
+[[Category: Edwards, A M]]
+[[Category: Liu, Y]]
 [[Category: Min, J]]
-[[Category: Liu, Y]]
+[[Category: Structural genomic]]
-[[Category: Bountra, C]]
 [[Category: Tempel, W]]
-[[Category: Arrowsmith, C.H]]
-[[Category: Edwards, A.M]]
-[[Category: Structural Genomics Consortium (Sgc)]]
 [[Category: Weigelt, J]]
+[[Category: Sgc]]
+[[Category: Transcription]]