5k2b: Difference between revisions
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==2.5 angstrom A2a adenosine receptor structure with MR phasing using XFEL data== | |||
<StructureSection load='5k2b' size='340' side='right' caption='[[5k2b]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5k2b]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K2B FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k2a|5k2a]], [[5k2c|5k2c]], [[5k2d|5k2d]]</td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k2b OCA], [http://pdbe.org/5k2b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k2b RCSB], [http://www.ebi.ac.uk/pdbsum/5k2b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k2b ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Aquila, A]] | |||
[[Category: Barty, A]] | [[Category: Barty, A]] | ||
[[Category: Batyuk, A]] | |||
[[Category: Boutet, S]] | |||
[[Category: Cherezov, V]] | |||
[[Category: Fromme, P]] | |||
[[Category: GPCR, GPCR Network]] | |||
[[Category: Galli, L]] | [[Category: Galli, L]] | ||
[[Category: | [[Category: Gati, C]] | ||
[[Category: | [[Category: Han, G W]] | ||
[[Category: | [[Category: Hunter, M S]] | ||
[[Category: Ishchenko, A]] | [[Category: Ishchenko, A]] | ||
[[Category: | [[Category: James, D]] | ||
[[Category: | [[Category: Katritch, V]] | ||
[[Category: | [[Category: Lee, M Y]] | ||
[[Category: Li, C]] | [[Category: Li, C]] | ||
[[Category: | [[Category: Liang, M]] | ||
[[Category: Liu, W]] | [[Category: Liu, W]] | ||
[[Category: | [[Category: Liu, Z J]] | ||
[[Category: Nelson, G]] | [[Category: Nelson, G]] | ||
[[Category: Popov, P]] | [[Category: Popov, P]] | ||
[[Category: Pu, M]] | [[Category: Pu, M]] | ||
[[Category: | [[Category: Spence, J C.H]] | ||
[[Category: Stauch, B]] | [[Category: Stauch, B]] | ||
[[Category: | [[Category: Stevens, R C]] | ||
[[Category: Weierstall, U]] | |||
[[Category: White, T A]] | |||
[[Category: Zhao, Y]] | |||
[[Category: A2a adenosine receptor]] | |||
[[Category: Gpcr]] | |||
[[Category: Gpcr network]] | |||
[[Category: Membrane protein]] | |||
[[Category: Psi-biology]] | |||
[[Category: Structural genomic]] | |||