5d7h: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5d7h is ~~ON HOLD until Paper Publication~~

==X-RAY CRYSTAL STRUCTURE OF L,D TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS==

~~Authors~~: ~~Saavedra~~, H., ~~Basta~~, L.A., ~~Lamichhane~~, G., ~~Bianchet, M~~.A.

== Structural highlights ==

<table><tr><td colspan='2'>[[5d7h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D7H FirstGlance]. <br>

~~Description~~: ~~X-RAY CRYSTAL STRUCTURE OF~~ L,~~D TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d7h OCA], [http://pdbe.org/5d7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d7h RCSB], [http://www.ebi.ac.uk/pdbsum/5d7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d7h ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/LDT2_MYCTO LDT2_MYCTO]] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection.<ref>PMID:20305661</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Basta, L A]]

[[Category: Bianchet, M A]]

[[Category: Lamichhane, G]]

[[Category: Saavedra, H]]

[[Category: ~~Bianchet, M.A]]~~

[[Category: Transferase]]

~~[[Category: Basta, L.A]]~~

~~[[Category: Lamichhane, G~~]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5d7h is ON HOLD  until Paper Publication
+==X-RAY CRYSTAL STRUCTURE OF L,D TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS==
+<StructureSection load='5d7h' size='340' side='right' caption='[[5d7h]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
-Authors: Saavedra, H., Basta, L.A., Lamichhane, G., Bianchet, M.A.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5d7h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D7H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D7H FirstGlance]. <br>
-Description: X-RAY CRYSTAL STRUCTURE OF L,D TRANSPEPTIDASE 2 FROM MYCOBACTERIUM TUBERCULOSIS
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d7h OCA], [http://pdbe.org/5d7h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d7h RCSB], [http://www.ebi.ac.uk/pdbsum/5d7h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d7h ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/LDT2_MYCTO LDT2_MYCTO]] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems. Is essential for virulence in a mouse model of acute infection.<ref>PMID:20305661</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Basta, L A]]
+[[Category: Bianchet, M A]]
+[[Category: Lamichhane, G]]
 [[Category: Saavedra, H]]
-[[Category: Bianchet, M.A]]
+[[Category: Transferase]]
-[[Category: Basta, L.A]]
-[[Category: Lamichhane, G]]