5l0o: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 5l0o is ON HOLD~~

==IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions==

~~Authors: Liu, J., Worthylake, D.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5l0o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L0O FirstGlance]. <br>

~~Description:~~ IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i6x|3i6x]]</td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0o OCA], [http://pdbe.org/5l0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l0o RCSB], [http://www.ebi.ac.uk/pdbsum/5l0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0o ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN]] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Liu, J]]

[[Category: Worthylake, D]]

[[Category: Calponin homology]]

[[Category: Disulfide-bonded dimer]]

[[Category: Signaling protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5l0o is ON HOLD
+==IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions==
+<StructureSection load='5l0o' size='340' side='right' caption='[[5l0o]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
-Authors: Liu, J., Worthylake, D.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5l0o]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L0O FirstGlance]. <br>
-Description: IQGAP1 calponin homology domain fragment (CHDF) mutant K161C under oxidizing conditions
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i6x|3i6x]]</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l0o OCA], [http://pdbe.org/5l0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l0o RCSB], [http://www.ebi.ac.uk/pdbsum/5l0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l0o ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/IQGA1_HUMAN IQGA1_HUMAN]] Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.<ref>PMID:15695813</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Liu, J]]
 [[Category: Worthylake, D]]
+[[Category: Calponin homology]]
+[[Category: Disulfide-bonded dimer]]
+[[Category: Signaling protein]]