5jfg: Difference between revisions
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==Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA== | |||
<StructureSection load='5jfg' size='340' side='right' caption='[[5jfg]], [[Resolution|resolution]] 1.77Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5jfg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JFG FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jfg OCA], [http://pdbe.org/5jfg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jfg RCSB], [http://www.ebi.ac.uk/pdbsum/5jfg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jfg ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU]] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Abell, C]] | |||
[[Category: Blundell, T L]] | |||
[[Category: Fischer, G]] | |||
[[Category: Hyvonen, M]] | |||
[[Category: Marsh, M]] | |||
[[Category: Morgan, M]] | |||
[[Category: Moschetti, T]] | |||
[[Category: Ng, H]] | |||
[[Category: Scott, D]] | |||
[[Category: Sharpe, T]] | |||
[[Category: Skidmore, J]] | |||
[[Category: Venkitaraman, A]] | |||
[[Category: Dna repair]] | |||
[[Category: Fragment based drug design]] | |||
[[Category: Humanisation]] | |||
[[Category: Hydrolase]] | |||
Revision as of 18:46, 26 October 2016
Structure of humanised RadA-mutant humRadA22F in complex with peptide FHTA
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