5t1j: Difference between revisions

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'''Unreleased structure'''


The entry 5t1j is ON HOLD  until Paper Publication
==Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet==
 
<StructureSection load='5t1j' size='340' side='right' caption='[[5t1j]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
Authors: Liu, C.F., Brandt, G.S., Hoang, Q., Hwang, E.S., Naumova, N., Lazarevic, V., Dekker, J., Glimcher, L.H., Ringe, D., Petsko, G.A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5t1j]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5T1J FirstGlance]. <br>
Description: Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5t1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t1j OCA], [http://pdbe.org/5t1j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5t1j RCSB], [http://www.ebi.ac.uk/pdbsum/5t1j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5t1j ProSAT]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TBX21_MOUSE TBX21_MOUSE]] Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs (By similarity).
__TOC__
</StructureSection>
[[Category: Brandt, G S]]
[[Category: Dekker, J]]
[[Category: Dekker, J]]
[[Category: Glimcher, L H]]
[[Category: Hoang, Q]]
[[Category: Hoang, Q]]
[[Category: Glimcher, L.H]]
[[Category: Hwang, E S]]
[[Category: Petsko, G.A]]
[[Category: Lazarevic, V]]
[[Category: Lazarevic, V]]
[[Category: Liu, C F]]
[[Category: Naumova, N]]
[[Category: Petsko, G A]]
[[Category: Ringe, D]]
[[Category: Ringe, D]]
[[Category: Naumova, N]]
[[Category: Dna binding]]
[[Category: Brandt, G.S]]
[[Category: Dna looping]]
[[Category: Hwang, E.S]]
[[Category: Master regulator]]
[[Category: Liu, C.F]]
[[Category: T-bet]]
[[Category: Tbox]]
[[Category: Tbx21]]
[[Category: Transcription factor]]
[[Category: Transcription-dna complex]]
[[Category: Transcriptional regulation]]
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