1pup: Difference between revisions
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|PDB= 1pup |SIZE=350|CAPTION= <scene name='initialview01'>1pup</scene>, resolution 1.700Å | |PDB= 1pup |SIZE=350|CAPTION= <scene name='initialview01'>1pup</scene>, resolution 1.700Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene> | |LIGAND= <scene name='pdbligand=APN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-ADENINE'>APN</scene>, <scene name='pdbligand=CPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-CYTOSINE'>CPN</scene>, <scene name='pdbligand=GPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-GUANINE'>GPN</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TPN:2-AMINOETHYLGLYCINE-CARBONYLMETHYLENE-THYMINE'>TPN</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1pup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pup OCA], [http://www.ebi.ac.uk/pdbsum/1pup PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1pup RCSB]</span> | |||
}} | }} | ||
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[[Category: Kastrup, J S.]] | [[Category: Kastrup, J S.]] | ||
[[Category: Rasmussen, H.]] | [[Category: Rasmussen, H.]] | ||
[[Category: dna analogue]] | [[Category: dna analogue]] | ||
[[Category: double helix]] | [[Category: double helix]] | ||
[[Category: peptide nucleic acid]] | [[Category: peptide nucleic acid]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:04:47 2008'' | ||
Revision as of 20:04, 30 March 2008
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| 1pup, resolution 1.700Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | APN, CPN, GPN, NH2, TPN | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION
Overview
The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself.
About this Structure
1PUP is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution., Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE, Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:9033585
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